Generic Name : Clomiphene
Brand Name : Clomid
Manufacturer : Aventis Pharma(Brand), Biolab-Ovinum(Brand)
| Product Name |
Price |
Order link |
| Clomid (Brand) 50 mg - 30 Tabs by Aventis Pharma |
$118.00 |
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Clomid-Ovinum(Brand)-Clomiphene Citrate(Generic) 50 mg - 30 Tabs by Biolab
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$58.00
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Clomiphene is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release 1 or more eggs.
Do NOT use Clomiphene if:
- you are allergic to any ingredient in Clomiphene
- you are pregnant
- you have abnormal vaginal bleeding
- you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome
- you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body
- you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (eg, pituitary gland tumor)
Clomid is used to induce ovulation (egg production) in females who do not produce ova (eggs) but wish to become pregnant.
Clomiphene Citrate is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Clomiphine citrate (Clomid) is a compound that is very similar in structure to estrogen. Because of this likeness, Clomid is able to bind to estrogen receptors in the hypothalamus.
This prevents the brain from seeing the negative signal from estrogen that is being released by the ovaries. As a result, the hypothalamus continues to stimulate the pituitary gland to make follicle stimulating hormone (FSH) and luteinizing hormone (LH). These hormones stimulate follicular growth in the ovary.
Clomid is administered orally in 50 mg increments (50, 100, 150) over five days. There are two common regimens for administration.
Using the first day of menses as cycle day one, Clomid is taken on days three to seven or days five to nine. If follicular monitoring is used, an ultrasound is usually done on day 10 (if taken on days three to seven) or day 12 (if five to nine). The actual release of the follicle using human chorionic gonadotropin (HCG) is timed when the follicles reach optimal size.
In general 50 mg is the usual starting dose. With a poor response, the dose is usually increased in steps. Polycystic ovarian disease and obesity may decrease the response to Clomid, but this is unpredictable and a starting dose of 50 mg is still recommended.
Of the pregnancies that occur using Clomid, 85 percent will occur in three months, and 99 percent will occur within five months. Treatment beyond five months is generally not seen as useful.
There are various adjuncts that can be used with clomiphine citrate. Among these are glucocorticoids, naltrexone, avandia, and metformin. These therapies are often not utilized to their full potential due to the wide availability of and effectiveness of gonadotropins.
Clomid can be used with or without monitoring of follicular growth. There are some physicians who have a bias about monitoring follicular growth with ultrasounds while others argue regular intercourse around the time of projected ovulation is adequate. Some individuals are given a prescription for Clomid to enhance ovulation over three to four months with a follow-up visit if they are not pregnant.
Some form of monitoring, LH predictor kits, day 21 progesterone (more accurate if drawn seven days post ovulation), or ultrasound monitoring, may be useful to demonstrate a response to the medication.
Since Clomid is a drug used for controlled ovarian hyperstimulation (COH), it may be combined with intercourse, cup inseminations, or intrauterine insemination.
Side effects are infrequent but can be serious. See medication risks for more details.
The average cost for clomiphine citrate is $10 per pill or $50 per month. Contact your pharmacy for more accurate pricing.
Clomid is a drug given to women for use as a fertility aid. It is a SERM (Selective Estrogen Receptor Modulator) which acts by actually binding to the estrogen receptor and thereby blocking estrogen from doing the same. Clearly, this is advantageous when it binds to breast tissue, and prevents estrogen from binding there to cause gynocomastia (although it is not nearly as effective as nolvadex for this purpose). It also opposes the negative feedback loop that the body has with regards to estrogen and the HPTA
(Hypothalamic-Pituitary-Testicular-Axis), and this in turn stimulates LH (Leutenizing Hormone) and FSH (Follicle Stimulating Hormone). LH and FSH, in turn stimulate the release of testosterone. Clearly this is advantageous to bodybuilders and athletes coming off of a cycle, and beginning their post-cycle-therapy. What we have in Clomid is essentially a drug that acts as a preventative measure against gynocomastia, as well as a drug that acts to raise endogenous (natural) testosterone levels. Usually, it is compared
with another SERM, Nolvadex, for those reasons.
Clomid, however, is much weaker than nolvadex in a mg for mg comparison, with roughly 150mgs of clomid being equal to 20mgs of nolvadex (1).It should be noted, however, that 150mgs of clomid will still raise testosterone levels to approximately 150% of baseline value(1). You don?t have to use 150mgs, however; in my research, I?ve found that doses as low as 50mgs will show improvements and elevations in testosterone levels (4). In fact, my original Post-Cycle-Therapy regime (as suggested by Dan Duchaine in
the original Underground Steroid Handbook) was 100mgs per day for a week and 50mgs/day for a week. Don?t laugh& for the late 90?s, when most anabolic steroid users didn?t even know how to use Clomid, it was considered a "state of the art" PCT routine. I suspect that Duchaine originally introduced this compound to the steroid using community.
Clomid, just like nolvadex, is very safe for long term treatment of lowered testosterone levels (2), with some studies showing its safety and efficacy for up to four months. And post-cycle, when steroid users are suffering form lowered testosterone levels, is when clomid is most effective.
I used to run Clomid for about 3 weeks post cycle, at 100-150mgs. Any more than that, and I experience emotional side effects (no, really) due to the excess amount of circulating estrogen I have in my body. All of that extra estrogen tends to make me moody, and it gets hard to squeeze workouts and cardio in-between reruns of "Sex & the City" (ok, I?m exaggerating).
Clomid Side Effects
A problem arose during a very aggressive Clomid PCT routine once. I was taking pretty high doses (150mgs/day) of clomid for an extended time (over a month) and was having vision issues. When I looked into the subject more closely, this was a common occurrence with steroid.com members. Upon further investigation, I found out the optic neuropathy (a fancy way of saying "vision problems") was actually very common with clomid usage (5)(6).Since I already wear contact lenses, I?ve had to remove Clomid
from my PCT routine.
Clomid Success
Clomid as of late has fallen out of favor for post-cycle routines, but if you aren?t prone to vision problems or emotional issues, then it is just as good as nolvadex for raising testosterone when appropriate doses are used. I recommend using 150mgs/day for ten days, and decreasing the dose by 50mgs every ten days until you?re finished at day 30. Many of the bodybuilders and athletes I?ve spoken to have used it in a similar fashion and found that it restores their testosterone levels to normal.